| New Anti Mitochondrial Antibody Method |
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Effective from 28th September 2009, the methodology of Anti Mitochondrial Antibody measurement will be changed to immunoassay.
The method for confirmation of mitochondrial antibodies has been changed from in-house immunoblot for antibodies to a commercial line immunoassay that detects antibodies to a purified mitochondrial antigen (AMA-M2) and a recombinant fusion protein (M2-3E).
This assay demonstrates improved sensitivity compared to the previous method and either AMA-M2 or M2-3E has demonstrated 97% specificity for diagnosis of Primary Biliary cirrhosis on a large serum bank performed retrospectively.
If you have any questions, please contact the immunology laboratory on 93428000 or Dr Gary Unglick Gary.Unglick@mh.org.au. | 
